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HOLOWA Core-Shell Column



HOLOWA Core-Shell Column, featuring a core-shell structure with a solid inner core and a porous outer layer, also known as Fused-Core technology. This advanced packing material offers high column efficiency, rapid analysis speeds, and low backpressure. It provides superior separation and peak shape for basic compounds, enhanced selectivity for structurally similar analytes, higher temperature tolerance, and a wider pH stability range.

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Advantages and Characteristics of HOLOWA Core-Shell Columns:

  • Innovative Core-Shell Technology: Featuring a porous silica shell fused onto a solid silica core.

  • Ultra-Fast Speed: Significantly reduced analysis times.

  • Ultra-High Column Efficiency: Exceptional theoretical plate counts for superior resolution.

  • Extended Service Life: Enhanced durability and long-term stability.

  • HPLC to UPLC Performance: Enables standard HPLC systems to achieve UPLC-level performance.

  • UPLC Optimization: Enhances the separation power, analysis speed, and robustness of UPLC systems.

  • LC-MS Sensitivity: Optimized flow dynamics and peak capacity for increased LC-MS sensitivity.

Available in various specifications

Column

Pore Size (Å)

Particle Size(mm)

Stationary Phases

Application Examples

HOLOWA

90

1.9

2.7

5

C18

AQ-C18

C8

RP-Amide

Phenyl-Hexyl

PFP

ES-CN

Penta-HILIC

HILIC (silica)

Biphenyl (NEW)

Small molecules

HOLOWA Peptide

150

2.7

ES-C18

ES-CN

Phenyl-Hexyl

Peptides & polypeptides

HOLOWA Protein

300 / 1000

2.7

C4, C8, C18

 ColumnPore Size (Å)Particle Size (μm)Stationary PhasesApplication ExamplesHOLOWA901.9, 2.7, 5C18, AQ-C18, C8, RP-Amide, Phenyl-Hexyl, PFP, ES-CN, Penta-HILIC, HILIC (Silica), Biphenyl (NEW)Small moleculesHOLOWA Peptide1502.7ES-C18, ES-CN, Phenyl-HexylPeptides & PolypeptidesHOLOWA Protein300 / 10002.7C4, C8, C18Peptides, Polypeptides, Small proteins, Large proteins, mAbs

 

Ultra-fast, ultra-high efficiency separation

Comparison between HOLOWA-2.7 and 3μm conventional C18

 

 

 

Nao'an Capsules

 

 

Other details:
  • Transportation:By air if not specified.